DNA Design and Science

DNA Design and Science

Most of us know that we have something called genes that determine our physical characteristics, which pass on to our children. Genes are pieces of a molecule called deoxyribonucleic acid (DNA). This molecule consists of two chains of alternating sugar and phosphate groups that coil around each other to form a double helix. These simple units line up in that double helix in a way that carries information much like the pages of a huge book. The DNA design carries much of the information that makes us who we are.

The complexity of the DNA molecule is astounding, and its size is even more so. If all the DNA molecules in your body were uncoiled and laid end-to-end, it would stretch from here to Pluto and back. Humans do not have the largest DNA molecules. A flowering plant native to Japan called Paris Japonica has a DNA molecule 50 times longer than human DNA. 

DNA was discovered in 1869 by Swiss Biochemist Friedrich Miescher, who called it nuclein. In the early 1940s, bacteriologist Oswald Avery discovered DNA’s connection to genetics. James Watson and Francis Crick discovered the double-helix structure of DNA design in 1953. 

Because the molecule is so large and complex, the opportunities to study it and make practical use of it are almost limitless. Scientists are using synthetic DNA to create vaccines. Some DNA vaccines have been successful in animals. At this time, some scientists around the world are working on COVID-19 vaccines using DNA.

Scientists are developing other uses for DNA coding. The Consortium for the Barcode of Life (CBOL) is working to establish barcodes to identify plant and animal species. The use of DNA has solved many criminal investigations. Modification of DNA has given us genetically modified foods.

There are two lessons we can learn from this. First, the complexity of DNA design boggles the mind. Suggesting that it is the product of random chance seems much less likely than the idea that an intelligence designed it. That leads us to the question of whether we are playing God in some DNA experiments. We have previously talked about genetically modified babies. The extreme complexity of DNA makes it much more likely for a human error, causing harm to others. Scientists working with DNA manipulation should be guided by reverence for the Creator and the life that He created.

— John N. Clayton © 2020

Body Repair System at Work

Body Repair System at Work

Advertisements for food supplements, diet plans, and “miracle cures” on the internet and television, in magazines, and newspapers continuously remind us that things in our environment threaten our existence. We are indeed attacked by human-made toxins, natural toxins, air and water pollution, ultraviolet radiation and x-rays from the Sun, and contaminants in the foods we eat. We have a natural body repair system that takes care of most of those threats.

The chemistry of the human body is an incredibly complex system in which a wide variety of chemicals keep us alive. There are 60-trillion cells in an average human body, and each cell has a chemical signature for what it does. Cells in your pancreas produce insulin and pump it into your bloodstream. Your thyroid produces a chemical that governs your metabolism. Your bone marrow and thymus gland produce antibodies that ward off disease. Those are only a few examples of the body repair system.

Most cells have thousands of chemical reactions going on at any given moment. The facilitators of this chemical system are proteins called enzymes. For every one of the thousands of chemical reactions that go on in each cell of your body, there is one specific protein molecule. It has just the right shape to bring two other molecules together and form bonds. That means there are massive numbers of enzymes to fill that role.

Our DNA contains the blueprints for making the enzymes, and our cells use those blueprints to make the proteins they need. If a cell is damaged, it dies, and another cell replaces it. If the DNA is damaged, then bad information is fed to the cells, and the result can be catastrophic. To avoid that problem, our DNA has segments known as genes. Each of the roughly 80,000 genes in the human body carries the information to assemble one enzyme and control one chemical reaction in the cell. This one enzyme can repair damage in the DNA, so the number of things that can kill a cell is significantly reduced by the body repair system.

Scientists are very interested in repair enzymes and how they keep our DNA functional. God has designed a system that enables us to live. Understanding that design is opening the door for new ways to cure the ills of humanity. Biochemists are researching and designing treatments for various genetic diseases. Reading about this kind of research always brings back the statement of David in Psalms 139:14, “I am fearfully and wonderfully made, marvelous are your works…”

— John N. Clayton © 2020

Genes and Addiction

Genes and Addiction Ozzy OsbourneSince the first sequencing of the human genome in 2003, there have been exhaustive studies of links between the human gene structure and addiction. Discover Magazine published a report on genes and addiction (November 2019 issue) with a summary of the current findings.

The magazine focuses on Ozzy Osbourne, the singer/songwriter and reality TV star who is sometimes called “The Godfather of Heavy Metal.” He is famous for going on binges of alcohol, Vicodin, cocaine, and other drugs that would kill most humans. He has survived to be 70 years old. The question is why Osbourne was able to survive all of this abuse for such a long time. One major factor seems to be a mutation in the ADH4 gene. The ADH4 makes a protein called alcohol dehydrogenase 4, which breaks down alcohol. The researchers have concluded that Osbourne is six times more likely to have an alcohol dependency than the average person because alcohol has a minimal effect on him.

The question arises of what are the links between genes and addiction to alcohol and other substances. The Food and Drug Administration says that one in every 12 adults in the United States suffers from alcohol abuse or dependence. Americans spend $200 million a day on alcohol, and 100,000 people die each year from accidents linked to alcohol. People of East Asian descent have an increase in heart rate when consuming alcohol. That effect is called “Asian Flush” or “alcohol flush reaction.” Researches have also found genetic links to anandamide, which is a brain chemical that affects mood and anxiety. Marijuana doesn’t affect people with mutations that alter the amount of anandamide in the brain.

This newfound information tells us a lot about how mutations have shaped how we behave in our consumption of different chemicals. Obviously, if a person doesn’t consume the chemical, the mutations are not an issue. For some people, this information enables them to justify blaming God for their addiction. There are drugs like disulfiram, which cause people to have an unpleasant reaction to the consumption of alcohol. However, using a drug to counteract a destructive drug is a poor solution to the overall problem.

The mutations that have caused all of this are man-made. The mutations are linked to a variety of human enterprises, including the distillation of alcohol. In the distant past, addition was not much of an issue, because the chemical effect of undistilled alcohol is minimal. Alcohol is a drug, and it needs to be identified as such. God has not caused the mutations, and humans are responsible for virtually all of the drugs that are causing so much pain and destruction.

So there is a connection between genes and addiction, and science is looking for ways to change the human genome to exclude the mutations. The biblical solution is to form a relationship with God that leads us away from the destructive forces around us. At the same time, we need to reach out to those who are struggling with their addictions and help them find a way out of their lifestyle of abuse. Walking in the light (1 John 1) involves a conscious change that leads to a new life (Romans 6). God did not lead us to destructive lifestyles, but He will help us build a newness in our lives if we are willing to turn things over to Him.
— John N. Clayton © 2019

Neanderthal Genes

Neanderthal Genes
There has been a lot of confusion about the Neanderthals in both religious publications and scientific writings. Scientists have reported that there are Neanderthal genes in modern humans.
Many have treated the Neanderthals as ape-men, and there have been multiple theories about how they originated.

Religious publications have speculated about Neanderthal influence on biblical characters. Those who wish to find “giants” in biblical accounts have claimed that the Neanderthals were giants, and at least one set of fake pictures of huge skulls has circulated on the internet attempting to back that up.

Researchers in Germany have just reported on DNA studies of the Neanderthal genes in modern humans. They found 15 Neanderthal DNA traits in modern humans. What is interesting is that these 15 traits show up in people of British ancestry, but people of pure African descent have no Neanderthal DNA. This will certainly complicate some of the “out of Africa” theories about the origin of humans.

We suggest that most of the claims of prehistoric humans involve racial variations. No claim of different species of humans is supported by the evidence. The biblical claim that Eve is the mother of all humans (Genesis 3:20) continues to be strongly supported as we study our past.
–John N. Clayton © 2017