The Thymus Has an Essential Purpose

Human Thymus Anatomy

A mysterious organ of the human body lies behind the sternum (breastbone) and in front of the heart. It’s called the thymus. Almost 2000 years ago, the Greek physician and surgeon Galen of Pergamon called it the “seat of the soul.” However, as recently as 1961, Nobel Prize-winning British biologist Sir Peter Medawar called the thymus the graveyard for dying cells and “an evolutionary accident of no very great significance.” Today, scientists know that the thymus has an essential purpose in establishing the immune system during childhood and continues to be beneficial throughout life. Since the thymus has been known for thousands of years, why did it take so long for science to discover that it has a purpose?

Recent research at Massachusetts General Hospital has shown the role the thymus plays in a person’s health. It helps regulate aging and immune health. It appears to play a crucial role in a person’s longevity, protecting against cancer, autoimmune disease, and even cardiovascular risks. Medical scientists have found that people with healthier thymuses are less likely to develop lung cancer or die of heart disease or other causes.

The thymus has sometimes been removed because it can get in the way of heart or chest surgery, and the removal is called a thymectomy. In the past, thymectomy was not considered a problem because people seemed to get along very well without the thymus. The research team found that people receiving a thymectomy were more likely to die of any cause within five years than people with a healthy thymus. People without a thymus were twice as likely to develop cancer and were also more likely to develop autoimmune disease.

The thymus has an essential purpose and is not a vestigial organ, as some have thought in the past. It is not a mistake of evolution. A healthy thymus is a predictor of good health in many respects. People with healthy thymuses are less likely to develop lung cancer or die of heart disease. They are also more likely to respond positively to cancer drugs. The research has led to interest in finding ways to slow the thymus’s natural deterioration, which occurs in adulthood.

Too often, we have been led to believe that something is a vestigial organ, leftover from the process of evolution, when, in fact, it plays a role in our health. (For example, tonsils, appendix, and so-called “junk DNA.”) Looking at medical research from an evolutionary viewpoint can sometimes lead to neglect of important health issues. If we believe our bodies are intelligently designed rather than merely accidents of evolution, we have a reason to look for that design. The thymus has an essential purpose because God designed it that way, but science overlooked it for way too long.

— Roland Earnst © 2026

References: washingtonpost.com, and New England Journal of Medicine HERE and HERE

The Thymus and Adult Health

The Thymus and Adult Health

New research shows a connection between the thymus and adult health. When I was a child in the early 1940s, doctors performed surgeries on children to remove a gland or organ because they thought it was vestigial and no longer needed. By the time I was in high school, my tonsils, adenoids, and appendix had all been removed. When my daughter Wendy became a teenager, she had repeated throat issues and infections. Her doctor refused to remove her tonsils or adenoids even though they were infected and hurting her repeatedly.

We know now that the tonsils and adenoids are an important part of the lymphatic system, keeping our bodies healthy by trapping harmful bacteria and viruses. As we have come to understand the immune system in humans, we have found that surgically removing the tonsils and adenoids can open us to infections. New research indicates the same is true of the thymus.

The thymus is a gland in the chest between the lungs, in front of and above the heart. It produces immune cells called T cells that protect against foreign invaders that could cause illness. In children, the thymus is very active, but after puberty, it shrinks. By then, the body has memory T cells specialized in attacking intruders the body has fought before. Since the thymus gradually becomes smaller, it is frequently removed in heart operations because it gets in the way.

Oncologist David Scadden and colleagues at Massachusetts General Hospital in Boston researched the thymus and adult health. They examined the health outcomes of 1,146 patients who had their thymus removed at the hospital between 1993 and 2020. They compared those with an equal number of patients who had the same surgeries but did not have their thymus removed. The death rate for those whose thymus was removed was three times higher than those who did not. Thymus removal was also associated with two times the risk of cancer within five years.

The thymus serves a purpose in childhood but may play a different role in adulthood. The researchers don’t know the cause of these striking numbers, but they show a strong connection between the thymus and adult health. We now know that the appendix, tonsils, and adenoids contribute to the body’s immune system to help keep us healthy. It appears that we should add the thymus to that list.

Psalms 139:14 says, “I will praise you, God, for I am fearfully and wonderfully made: marvelous are your works..” We don’t have to look far to see God’s wisdom and design in creation. Just look in the mirror.

— John N. Clayton © 2023

References: Science News for August 26, 2023, and New England Journal of Medicine