protein Archives - DOES GOD EXIST? TODAY

March 28, 2023March 27, 2023

Cells and Cities Show Purpose and Design

Whether we live in a city or in the country, we all recognize that cities are hubs of activity that keep life going and hopefully thriving. A living cell is like a miniature city, and we see life functions in the cell that correlate with activities that maintain life in the city. We can learn some things by comparing cells and cities.

A city has a boundary called the city limits, and cells have a membrane marking their outer boundary. At the city center, we have a city hall and courthouse storing vital information and sending out directives to keep the city functioning. Cells have a nucleus that performs similar functions. The nucleus contains DNA that stores all the information for constructing and controlling the cell’s components and, ultimately, the entire body.

Both cells and cities must have a way to transport materials within their boundaries. In cities, streets, roads, and highways perform this function. Cells have a transportation system called the endoplasmic reticulum (ER) to move proteins around and perform other functions. Both cells and cities need an energy source to function. Cities get their energy needs from fossil fuels, solar cells, and electrical generators. Mitochondria, “the powerhouse of the cell,” convert food calories into chemical and heat energy to maintain the cell’s life.

Garbage trucks and sewers remove waste in the city. Cells have structures called lysosomes filled with digestive enzymes that eliminate toxic materials. Cities have factories that produce the products people need. Protein factories in the cell are called ribosomes, which manufacture new structures according to the genetic instructions in the DNA.

While the U.S. Postal Service and companies such as UPS and FedEx transport materials between cities, the Golgi apparatus does that for the cells. For example, Golgi bodies in the pancreas package insulin for transport to other cells, allowing them to convert sugar into energy. Cells and cities need places to store essential commodities, and vacuoles perform that function in the cells.

We live in a city that was not built by random chance. Our city has a history of design that allowed Niles, Michigan, to be founded and developed. Just as Niles was not merely a product of chance, so too the cell is not an accident. In this comparison, we have greatly oversimplified our explanation of the cell functions since cells are even more complex than cities. If cities require design and purpose by intelligent beings, living cells give strong evidence of purpose and design by a wise creator God.

Inspired by: “Cells function like miniature cities” by Sheryl Myers in the Herald Bulletin of Anderson, Indiana, February 25, 2023

December 29, 2020January 3, 2021

Understanding Proteins and How They Are Made

How does insulin control blood sugar levels? How do antibodies fight coronaviruses? Questions like these have been at the frontier of biochemical research for as long as we have known there were such things as proteins. Understanding proteins and how they are made is a challenge that continues to be the focal point of a great deal of work.

The human body contains at least 20,000 different proteins, and their shapes are controlled by how their component amino acids are twisted and folded. In the medical field, the importance of understanding proteins is enormous. Not understanding proteins and how they are made would be like trying to fix a car engine when you don’t know how it works or how it was put together.

The Week for December 18, 2020, quotes Janet Thornton of the European Bioinformatics Institute, saying, “This is a problem that I was beginning to think would not be solved in my lifetime.” What has changed is that computers can do in hours what would take a human years to solve. Scientists have analyzed protein structures for malaria, sleeping sickness, and leishmaniasis (a disease caused by parasites) to find new methods of treating those diseases.

Amino acids are the basic building blocks of life, and we know that they exist in outer space and can be produced in the laboratory. Using these building blocks to make proteins that govern how life works is extremely complex. The amino acids bend and fold in origami-like structures to make proteins. To suggest that proteins can result from some chance process of organic evolution is stretching credibility to the breaking point.

Genesis gives us the simple statement, “And God said ‘It is good.’” As biochemistry begins understanding proteins and how they are made, we see how complex God’s creation is. Those simple words wonderfully describe what we are starting to understanding as a work of incredible intelligence and design.

August 28, 2020August 27, 2020

Blood Clotting Design

A couple of days ago, I accidentally sliced the tip of my finger with a sharp knife. It bled a lot for a while, but in a short time, the bleeding stopped. The bleeding probably helped cleanse any debris from the wound, but I didn’t want the bleeding to continue. If our blood did not clot, we could bleed to death from even a small injury. Blood clotting design, or coagulation, is a very complicated process that scientists have studied for years.

The process begins when a puncture to your skin injures a blood vessel exposing blood platelets to the collagen beyond the blood vessel’s lining. The platelets immediately bind to the collagen and each other, forming a temporary plug. This starts a whole series of complex chemical reactions involving proteins and enzymes called clotting factors.

A cascading series of a dozen steps must take place for coagulation to complete. The result is the creation of fibrin strands which strengthen the platelet plug and stop the bleeding. If any single factor of the clotting process is missing, the clot does not form, and the bleeding continues.

Hemophilia is a genetic defect that omits a clotting factor. It disrupts the process of blood clotting design such that people with hemophilia may bleed uncontrollably from even a small wound. This is an extremely simplified summary of the coagulation process involving a dozen factors requiring specific proteins and enzymes that must happen in a particular order. For more details, click HERE.

Without blood clotting, humans and other mammals could not have survived. All of the clotting factors had to be present at the beginning of mammal and human life, meaning that the coagulation process could not develop gradually by chance. The fact that our blood clots when we are injured is another evidence of design by an intelligent Creator.

June 1, 2020May 31, 2020

Body Repair System at Work

Advertisements for food supplements, diet plans, and “miracle cures” on the internet and television, in magazines, and newspapers continuously remind us that things in our environment threaten our existence. We are indeed attacked by human-made toxins, natural toxins, air and water pollution, ultraviolet radiation and x-rays from the Sun, and contaminants in the foods we eat. We have a natural body repair system that takes care of most of those threats.

The chemistry of the human body is an incredibly complex system in which a wide variety of chemicals keep us alive. There are 60-trillion cells in an average human body, and each cell has a chemical signature for what it does. Cells in your pancreas produce insulin and pump it into your bloodstream. Your thyroid produces a chemical that governs your metabolism. Your bone marrow and thymus gland produce antibodies that ward off disease. Those are only a few examples of the body repair system.

Most cells have thousands of chemical reactions going on at any given moment. The facilitators of this chemical system are proteins called enzymes. For every one of the thousands of chemical reactions that go on in each cell of your body, there is one specific protein molecule. It has just the right shape to bring two other molecules together and form bonds. That means there are massive numbers of enzymes to fill that role.

Our DNA contains the blueprints for making the enzymes, and our cells use those blueprints to make the proteins they need. If a cell is damaged, it dies, and another cell replaces it. If the DNA is damaged, then bad information is fed to the cells, and the result can be catastrophic. To avoid that problem, our DNA has segments known as genes. Each of the roughly 80,000 genes in the human body carries the information to assemble one enzyme and control one chemical reaction in the cell. This one enzyme can repair damage in the DNA, so the number of things that can kill a cell is significantly reduced by the body repair system.

Scientists are very interested in repair enzymes and how they keep our DNA functional. God has designed a system that enables us to live. Understanding that design is opening the door for new ways to cure the ills of humanity. Biochemists are researching and designing treatments for various genetic diseases. Reading about this kind of research always brings back the statement of David in Psalms 139:14, “I am fearfully and wonderfully made, marvelous are your works…”

April 7, 2020April 6, 2020

What Are Viruses and What Is their Purpose?

It is self-evident that we are all impacted by something called a “virus.” What are viruses, and what is their purpose?

The first clue about viruses was in 1898 when scientists discovered that the cause of foot and mouth disease in livestock was something smaller than any bacteria. Because viruses are about 100 times smaller than bacteria, they could not be detected until electron microscopes were developed in 1931. Since viruses were too small to be filtered out, scientists initially thought they were liquids. They were given the name “virus” which comes from the Latin word for poison.

Later, scientists discovered that a virus is a protein (DNA or RNA) molecule enclosed in a capsid covered by a protective layer of fat, or lipids. The virus in and of itself is inert and unable to reproduce. So what is their purpose? When they come in contact with living cells, they insert their genetic material into the host, so the cell now produces viral protein. This may produce harmful and life-threatening results. Among the illnesses generated by viruses are the common cold, influenza, smallpox, chickenpox, herpes, shingles, AIDS, polio, rabies, Ebola, and others.

If the protein is beneficial, the virus can produce a useful evolutionary change. In that way, viruses are tools to create new genetic products. In today’s world of genetic engineering, the process is called transduction. We have pointed out before that many times good things come from evolutionary change. God designed living things with the ability to change and adapt. Scientists use viruses as tools to affect desired genetic changes in agricultural products to produce high protein corn, for example. Some viruses attack bacteria, and they are called bacteriophages. As bacteria have developed resistance to antibiotics, scientists are interested in using bacteriophages as a defense against harmful bacteria.

If they are not living things, then what are viruses? They are sometimes called “organisms on the edge of life.” They are not fully living on their own, but they possess some characteristics of living things. Viruses are very fragile because the only thing protecting them is a thin layer of fat, known as lipids. If the fat is dissolved, the protein molecule disperses and breaks down on its own. That is why any soap or detergent will destroy a virus, and why washing your hands with soap and warm water is essential. Heat melts fat, so water above 25 degrees Celsius (77 degrees F) for washing clothes, dishes, or hands will destroy viruses. Any solution which is more than 60% alcohol will dissolve fat and destroy the virus, as will bleach in a 1 to 5 ratio to water. Antibiotics or bactericides do not affect a virus because they only work on living tissue. Antibiotics cannot kill what is not alive.

The problem with viruses is that when they are transferred from animals into humans, or even different animals, they can be destructive. Scientists believe that the current coronavirus (SARS-CoV-2) is active in bats where it causes no problems. When the virus jumped into humans, the result was destructive.

Then, what is their purpose? Viruses can be useful tools in their proper place. They are part of the way life continues to exist on a changing Earth. Mismanagement of animals and food can cause a virus to become an enemy of humans. We have a repeat of the Frankenstein phenomenon when a potentially useful concept turns into a monster because of misuse.

Data from: Berkeley.edu and wikipedia.org

January 8, 2020January 8, 2020

We Are Not a Product of Chance According to Yale Professor

Those who maintain that all life is a product of chance have a new opponent on their hands. He is Dr. David Gelernter, professor of computer science at Yale University, chief scientist at Mirror Worlds Technologies, and a member of the National Council of the Arts. He says that we are not a product of chance.

One of Dr. Gelernter’s main arguments is the difficulty of producing a stable and functional protein by blind, mechanical chance. Proteins are the work-horses of life. Proteins called enzymes catalyze all sorts of reactions and drive cellular metabolism. Other proteins, such as collagen, give cells shape and structure. Proteins drive nerve function, muscle function, and photosynthesis. The question is whether mindless, random changes in molecules can create all the different proteins necessary for life to exist.

The argument starts with amino acids, which we know can be formed by natural processes in specific environments. Statisticians calculate that the odds of amino acids forming a stable protein are 1 in 10⁷⁴. As Gelernter writes, “To say that your chances are 1 in 10⁷⁴ is not different, in practice, from saying that they are zero.” For comparison, science tells us there are only 10⁸⁰ atoms in the universe. Gelernter says, “The odds bury you. It can’t be done.”

It is essential to understand that we are not talking about the formation of life here. Gelernter is talking about making chance mutations in existing DNA that result in a useful new protein that could play a role in evolution. Macroevolution, or the creation of new species, would require new genes that could create a meaningful new protein. This is simply one small step in producing the materials necessary for life.

We are not a product of chance. There is growing evidence of the design and planning that has gone into the making of life and us. Dr. Gelernter says he has been attacked by some atheistic scientists, because, as he says, “I am attacking their religion.”

Reference: Spring 2019 issue of Claremont Review of Books titled “Giving up Darwin” and posted on line on May 1, 2019.

June 23, 2018June 12, 2018

Adding Nitrogen to the Soil

We all know that lightning can be dangerous. Each year people are killed, and a great deal of property damage occurs because of lightning. We don’t usually consider the benefits of this powerful force. Nitrogen in the soil is essential for plants to grow and lightning is a natural method of adding nitrogen to the soil.

Although lightning can be dangerous, it also produces materials that are critical to life. All living things depend on the chemical element nitrogen. Your body contains molecules known as proteins. Proteins are made up of several elements, including nitrogen. Nitrogen is essential for proteins, but it is very hard to make nitrogen into proteins. Even though nitrogen makes up 78 percent of our atmosphere, we don’t get any nitrogen from the air we breathe. With each breath, we inhale and exhale nitrogen without using it. The nitrogen in the atmosphere has three electron bonds between the atoms, and that is a very strong and stable chemical arrangement. It takes an enormous amount of energy to break those bonds to free the nitrogen.

When lightning slices through the atmosphere, it knocks electrons from nitrogen atoms. The atoms are then free to combine with oxygen and hydrogen in the atmosphere forming nitrates. Rain carries this new compound to the ground enriching the soil with nitrates which are the building blocks of proteins. Plants synthesize the nitrates into proteins. When animals eat the plants, they get proteins. When we eat the plants or animals, we get the proteins we need to build more proteins.

Without lightning and the other processes for adding nitrogen to the soil, life could not exist on Earth. There is a purpose in the design of lightning. The Designer has also given us the intelligence to avoid many of the adverse effects of this powerful force.
–Roland Earnst © 2018