How Cells Dispose of Waste – Autophagy

How Cells Dispose of Waste - Autophagy

If you remember your high school biology course, you may recall two organelles within the cell. One is mitochondria, which produce energy for the cell. The other is the endoplasmic reticulum which assembles the proteins to carry out the cell’s job. So naturally, any process as complex as those organelles do will produce some waste byproducts, some of which are toxic. Autophagy is the process of how cells dispose of waste.

In 2016 Dr. Yoshinori Ohsumi was awarded a Nobel Prize for his work in understanding the process. Autophagy degrades some mitochondria and carries out the removal of toxins. The name comes from Greek words that mean “self-eating.” New autophagy research is critical because disease prevention requires efficiently removing toxins from the cell. If autophagy is reduced or impaired, it can start or catalyze the growth of cancerous cells. Scientific understanding of how cells dispose of waste by autophagy may also improve the treatment of other diseases.

The description of autophagy we received in high school biology was greatly simplified, and even scientists today still have much to learn. According to current researchers, “the cell is a complex driver of machinery which is continually being built, put into motion, and eventually broken down.” We know that any machine must be carefully designed and manufactured in a controlled way. That means the living cell is a clear example of the complexity of life.

Creating life required clever engineering and great attention to detail. Autophagy is just one part of what God designed into all living cells. Proverbs 8 personifies “Wisdom” describing her involvement in God’s creative process. That wisdom is apparent in how cells dispose of waste.

— John N. Clayton © 2023

Reference: The journal Cell

Magnetotactic Bacteria Finding Their Way

Magnetotactic Bacteria Finding Their Way

Before GPS, people found their way with a compass. Many still do. Did you know that finding your way is possible, even if you don’t have any eyes or ears, or even a brain, as long as you have a compass? Magnetotactic bacteria (MTB) use the magnetic field of planet Earth to know which way to go. To do that, they have to build a compass. Realize that these are single-cell organisms that live in marine or freshwater habitats.

Inside the cells of all living things, there are subunits called organelles that perform various functions. MTB have organelles called magnetosomes that contain magnetic crystals. They build the magnetosomes by digesting iron and combining the iron with sulfur to form iron sulfide or with oxygen to form iron oxide. The iron oxide is also known as magnetite, and it’s a powerful magnet.

The bacteria form chains of these magnetic crystals inside their cells. The magnetosome chain acts as a compass needle aligning the MTB to Earth’s magnetic field. In this way, the magnetotactic bacteria can “know” the direction to move. Why do these bacteria need to know directions? They are anaerobic bacteria, meaning that they survive without oxygen. Oxygen can be deadly to them, so they need to find an area away from it. Rather than blindly going around in circles looking for a safe place, they move in a straight line to their anaerobic safe zone.

In 1963, an Italian scientist first noticed certain bacteria aligning and moving in the direction of the north pole. It wasn’t until 2007 that scientists paid much attention to that observation. Without eyes, ears, or a brain, magnetotactic bacteria can find where they need to go. But without a brain, how can they know to do this? And how can a single-cell bacterium build the magnetosome organelles? These magnetic crystals are difficult for humans to create in a laboratory. In fact, scientists have found that the magnetite produced by bacteria is better for some applications than what the scientists can produce in the laboratory. For that reason, they are looking to find a way to mass-produce MTB to obtain their magnetosomes.

Who taught the magnetotactic bacteria this fantastic skill? Did one of them figure it out and then pass that knowledge on to future generations? We don’t think so. A better explanation is that the Master Designer programmed the skill into them.

You can read a scientific paper on MTB at THIS LINK. Leading evolutionary biologist J.B.S. Haldane (1892-1964) once said that if you could find a magnetic mechanism as part of a living organism, it would disprove evolution. You can read more about Haldane and his statement at THIS LINK.

— Roland Earnst © 2020