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“Autoimmunity is the system of immune responses of an organism against its own healthy cells, tissues, and other body normal constituents. Any disease that results from such an aberrant immune response is termed an “autoimmune disease.” –Wikipedia

As many as 4.5% of the world’s population may be affected by any of about 80 autoimmune diseases. Some such as psoriasis are cosmetic, and others such as multiple sclerosis are life-threatening. So when the human body attacks itself, should we assume that it is because the body’s design is flawed? The exact cause of autoimmune disorders is unknown, but as more and more data becomes available, it is clear that this is not a flaw in the design of the immune system.

First of all, the number of autoimmune disorders that affect large populations is minimal. Psoriasis, Hashimoto’s thyroiditis, celiac disease, Graves disease, and rheumatoid arthritis are the most common, affecting one person out of every 100. Type 1 diabetes, vitiligo, and rheumatic fever can affect one person out of every 1000 or so. Most autoimmune diseases are infrequent, with some affecting fewer than 1 in a million people.

Secondly, we now know that some bacteria or viruses entering the human body from animals may confuse the immune system and lead to disorders. COVID and AIDS have shown us that animals are a source of viruses that can cause disease in humans.

Thirdly, chemicals can trigger changes in cells that the immune system is not designed to handle. Pesticides, herbicides, recreational drugs, industrial waste, and medical waste have caused all kinds of problems for humans. Immune disorders may not be because of bad design of the immune system but the result of human ignorance, carelessness, and greed.

Fourth, a new study has suggested that stress may lead to some autoimmune diseases, such as lupus or rheumatoid arthritis. There is a higher incidence of autoimmune diseases among people who were previously diagnosed with stress-related disorders.

God’s design of the human immune system is amazing. As the Psalmist said. “I am fearfully and wonderfully made” (Psalms 139:14). The immune system that allows most of us to live for many years with good health is one of the best demonstrations of the truth of that statement.

— John N. Clayton

See the September 2021 issue of Scientific American (pages 26-51) for much more information about autoimmune diseases, their causes, and potential cures. Pages 32 and 33 display a fascinating chart with data on 76 autoimmune disorders.

A new medical study is looking into something called the hygiene hypothesis.

Atheists often challenge the existence of God based upon their belief that the presence of diseases shows that there is no God. They conclude that an all-powerful God would not disease to exist. We have pointed out that a huge percentage of the maladies that afflict humans are the result of human abuse–pollution, drug use, foolish use of chemicals. etc. (See the doesgodexist.today posts for January 23, 2018; November 25, 2017; November 15, 2017; November 7, 2017; October 18, 2017).

Another dimension to the question of diseases is whether we have catalyzed the rates of contracting diseases by defeating the design of our immune system—the hygiene hypothesis. Major outbreaks of polio first began in the late 1800s. Multiple sclerosis doubled worldwide in the second half of the twentieth century. Type 1 diabetes rose dramatically in the 1950s. All of these diseases involve immune system problems.

In MS the immune system attacks the protective covering around certain nerve cells. In type 1 diabetes the body’s immune system destroys the cells in the pancreas that make insulin. The hygiene hypothesis says that exposure to various viruses or bacteria allows the immune system to protect the individual against what seem to be unrelated illnesses. It is not completely understood yet, but somehow the infections allow the developing body to learn how to deal with pathogens. The absence of exposure can prompt the immune system to attack the body itself.

In the early 1900s, one or two children under the age of 15 developed type 1 diabetes. In Finland, that number is now 60 children per 100,000. Between 1998 and 2010 the incidence of type 1 diabetes jumped by 40%. We need to point out that this is not caused by obesity. Type 1 diabetes happens in children who are not obese at the same rate as in those who are.

The evidence seems to indicate that there is a viral trigger and the type of viruses causing the diabetes are enteroviruses which are normally found in the intestines. A child exposed to those viruses at an early age develops a resistance to the enteroviruses and is not likely to contract the disease. If the viruses are not present in the environment, then later in life the immune system is defenseless against the enterovirus, and the immune system attacks the pancreas. At least, that is part of the hygiene hypothesis.

There is a great deal that science does not understand about how the immune system works. It is very complex, but it has worked remarkably well in humans throughout our history. Some of the diseases we are facing today seem to be occurring because the immune system of children has not been “tuned” by the viruses in the environment. Perhaps God’s design which served humans well in the past has been shut down by our rules for hygiene and the overuse of chemical agents. On the positive side, this study may eventually provide us with a vaccine which will eradicate the germ-caused diseases.

Tag: multiple sclerosis

Hygiene Hypothesis and Disease