Biological Clock Circadian Rhythm

Biological Clock Circadian Rhythm
Three scientists have just received Nobel Prize in medicine for proving scientifically something we knew all along. The scientists share the 1.1 million dollar prize for proving that we really do have a biological clock. The fact that you are alert at certain times and sleepy at others is not just in your head.

In 1984 they sequenced the “period gene” which others had discovered in fruit flies in 1971. The gene controls the circadian rhythm which regulates the daily sleep and wake patterns of all creatures, including humans. Following up on that work, in 1998 they found that the gene encodes a protein called PER. The PER levels build up at night and drop during the day. This discovery enables scientists to understand the molecular makeup of the biological clock.

Learning more about our biological clock leads to some useful understandings, including when is the best time to take certain medications. It also relates to shift work, jet-lag, and school classroom times. The understanding of circadian rhythms can be incorporated into practical medicine and the body’s production of melatonin, a hormone that prepares us for sleep.

A group of sleep researchers a few years ago did some research on biological clocks. They sent a group of volunteers on a tent-camping trip to the Colorado Rockies. They found that people who work indoors where they are not exposed to outdoor light may need to have their biological clocks reset. When people are indoors during the day and exposed to electric lights at night, their clock can become out of sync. Exposure to strong artificial light at night can delay our master clock. That delays the production of melatonin at night, and then the melatonin level is still high in the morning when it’s time to get up.

The campers were only allowed to use campfires for light and no cellphones or flashlights. After spending a week away from artificial light and exposed to more daylight, the volunteers fell asleep earlier and woke up earlier. Their melatonin levels rose earlier in the evening and dropped earlier in the morning.

The recommendation of the researchers was to start your day with a morning walk and when you have to be inside open the shades to get exposure to some sunlight. You may find that you will sleep better and wake up more refreshed.

“And God said, ‘Let there be lights in the expanse of the sky to separate the day from the night’…God set them in the expanse of the sky to give light on the earth, to govern the day and the night, and to separate light from darkness. And God saw that it was good” (Genesis 1:14, 17).
–Roland Earnst © 2017

God’s Provision for Food

God's Provision for Food
In the September 2017 issue of National Geographic, there is a very interesting article titled “A Tiny Country Feeds the World” by Frank Viviano. The article shows how the Netherlands has developed agriculture to such an extent that they not only can feed their own dense population (1300 inhabitants per square mile), but they have become the globe’s number two exporter of food. They are second only to the United States which has 270 times the amount of landmass. As many people in the world are starving, the work of the Dutch people reminds us of God’s provision for food.

Since 2000 the Dutch have increased production of food by applying their intelligence to the problem. By improved scientific methods, they have reduced their need for water for crops by 90%, virtually eliminated the use of chemical pesticides, and cut the use of antibiotics in livestock by 60%. They have done this by fully utilizing all of the resources available to grow food, and not allowing the negatives that humans have introduced. The Dutch growers use greenhouses where they can control the light, nutrients, and water. They waste nothing and allow no destructive agents. The food is still “natural” but without those things which cause us to add carcinogens to control insects and blight.

The Netherlands is also a major exporter of seeds. Their agricultural technology uses molecular breeding, rather than GMOs (Genetically Modified Organisms) to produce new seed varieties. Their method is faster and cheaper than GMOs, and the article says the method “is a direct descendant of methods used by farmers in the Fertile Crescent 10,000 years ago.” The Fertile Crescent, by the way, is the area of the Garden of Eden, bounded by the rivers which are still known today.

Projections are that by 2050 the Earth may have as many as 50 billion people to feed making is necessary for us to use all the intelligence as well as resources of God’s provision for food. We have the tools to do this, but it will take work and full utilization of God’s design to feed the world. God told Adam that he would eat by “the sweat of his brow.” God was saying it wouldn’t come easy, but He has taken care to provide the resources and tools to do it.
–John N. Clayton © 2017

Homeopathic Nonsense

Homeopathic Nonsense
There are many negative spin offs of the “evolution creation controversy” and the view that science and religion are opponents. One of the most destructive is the skepticism of natural medical remedies by opponents of religion, and the blind acceptance of them by believers.

Science and faith are friends, and science by definition is knowledge (see Webster’s Dictionary) and involves an organized way to arrive at facts. There are natural things that scientific research has shown to be useful in treating ailments and pain. Aspirin is a natural material that has many medical benefits, and some plants such as aloe help relieve sunburn. The list of tested natural materials that help us medically is very long.

Jesus pointed out that natural things can serve us in profitable ways. In Matthew 16:2-3 he told about the use of natural things to predict the weather. In 1 Timothy 5:23 Paul pointed out a use of the wine of that day for stomach problems. However, homeopathic nonsense originated in 1796 based on a false theory that “like cures like.” In other words, if you take something that causes an illness and dilute it with water or alcohol until there is nothing left of it, that dilute solution will cure the ailment.

One homeopathic “cure” is Boiron’s Oscillococcinum. The manufacturer claims that it cures cold and flu symptoms. Some drug stores sell it on the shelf with Tylenol. It has been marketed for years based on the false claim that Oscillococcinum is a bacteria that causes influenza. There is no bacteria by that name and colds and flu are caused by viruses and not by bacteria. The inventor claimed that he found the bacteria in patients with Spanish flu in 1917 and also in the liver of the Muscovy duck. The duck liver is diluted to one part duck liver with 10 to the 400th power parts of water. (That would be one followed by 400 zeroes, or virtually pure water.) Other ingredients (sucrose and lactose) are added to make it into pills. In other words, it is a sugar pill placebo.

Just because a product is “natural” doesn’t mean it gives any health benefits. Although many natural products do contribute to our health, many other natural products are toxic to the human body. God expects us to use evidence and common sense in applying what He has given us to treat our ailments, and we can start by avoiding homeopathic nonsense.
–John N. Clayton © 2017

Cancer Curse and God

Cancer Curse and God
One of the most common catastrophic illnesses facing humans is cancer. If you live long enough, it is almost sure that you will experience cancer in yourself or a loved one. Atheists contend that there can’t be a God or He wouldn’t allow the cancer curse to become so common and cause so much suffering.

A study recently released by Johns Hopkins University found that 29% of cancer-causing mutations result from environmental factors such as Sun exposure or cigarette smoking and inherited genetic mutations cause 5%. The remaining 66%, according to the study, are completely random and are due to bad luck. The authors of the study say they wanted to offer comfort to people with cancer who were living a healthy lifestyle, by showing that it was not their fault they got cancer.

This type of study has many problems. First, it involved 32 cancer types and 69 countries. The sampling of the study would have been extremely difficult because cancer incidence in areas with large amounts of asbestos in the soil and bedrock would be different from areas with no asbestos. The effect of exposure to toxins in the environment would vary widely. The ages of the subjects are also important because part of the cancer problem is that more people are living long enough to get cancer. That was not the case even 100 years ago.

When God created the first humans, there was no cancer problem. The point is that God did not create cancer. Passages like Deuteronomy 28 tell us that rejecting God would result in God not withholding “curses” on humans. Verses 1-14 describe God’s protection from these things, but verses 15-68 describe the curses in detail. The Hebrew word for curse in these verses is arar which means to be completely without God’s help or blessing.

When humans reject God, we are left on our own to deal with the consequences. Galatians 6:7-8 talks about reaping what we sow. That principle applies to people or nations as well as individuals. James 1:13-17 describes God as a loving God who never gives us temptations of any kind, but rather brings good things. It also tells us that God does not vary or mislead in the way He deals with us.

We have contaminated our world with chemicals that we disposed of in irresponsible ways. We have contaminated our bodies with chemicals from recreational drugs, alcohol, and even prescription drugs. The result has been a cancer curse and many of the curses God warned of in Deuteronomy. We need to turn back to Him.
–John N. Clayton © 2017

Medical Marijuana–Good or Bad

Medical Marijuana
All the discussion of medical marijuana and the questions of legalization are based on the assumption that people understand the endocannabinoid system (ECS) of the human body. The general public is almost universally unaware of this system, and yet it is a major player in the question of the use of medical marijuana.

In our brain and throughout our central and peripheral nervous systems we have receptors that are involved in appetite, pain sensation, mood, sleep, and memory. This complex system operates by chemical reactions with enzymes and molecules released by the system itself called endocannabinoids. When life experiences such as stress act on the brain, chemical secretions influence the ECS system and our behavior.

Marijuana contains phytocannabinoids which interact with the endocannabinoids which the body makes. The scientific name for marijuana is Cannabis sativa, and this plant contains more than 100 different cannabinoids as well as hundreds of other chemicals. The following cannabinoids have been studied enough to know what effect they have on the human brain:

Cannabidiols (CBD)

– painkiller, anti-inflammatory, antioxidant, anxiety reducer, antipsychotic, reduces muscle spasms

Tetrahydrocannabinols (THC)

– painkiller, anti-inflammatory, antioxidant, euphoriant, suppresses nausea and vomiting

Cannabigerols (CBG)

– painkiller, anti-inflammatory, antibiotic, antifungal

Cannabichromenes (CBC)

– painkiller, anti-inflammatory, antibiotic, antifungal

Cannabinols and Cannabinodiols (CBN, CBND)

– anti-inflammatory, antibiotic, sedative, anti-convulsant

Marijuana has a high potential for abuse, but it also has useful purposes. As we understand more about the design of our brain and nervous system, we will find ways that cannabinoids can be used to relieve human suffering. However, medical marijuana benefits do not come from smoking it which can damage the lungs and become addictive just as cigarette smoking does. Tests have shown that long-term use can lead to psychotic disorders, heart problems, and sexual/reproductive problems.

Marijuana itself is not evil, and certainly not a creation of Satan as some have implied. Humans can and do use marijuana as a destructive agent, but God designed it and intended it for good.
–John N. Clayton © 2017

Toxic Martian Cocktail

Toxic Martian Cocktail
Mars researchers have discovered a new issue in their attempts to find life on Mars—a toxic Martian cocktail.

One reason scientists believed that life might be possible on Mars was that tests from Martian soil samples show chemicals that are a potential energy source for bacteria. However, because Mars has such a thin atmosphere, ultraviolet radiation levels are very high. A Recent sampling of the Martian soil has also shown that it contains perchlorates, which are toxic to living cells. An article in Scientific Reports on Nature.com said that the UV rays combined with perchlorates as well as iron oxide and hydrogen peroxide together give what the researchers are calling a “toxic cocktail.” The bacteria Bacillus subtilis, which is often found in spacecraft and can survive extreme conditions of space, is wiped out in 30 seconds when exposed to this cocktail.

In other words, the surface soil on Mars can kill living cells. On July 6 Popular Science reported on these findings and indicated that you would have to go six feet below ground to get away from this toxic mix. Surface expressions of life on Mars are almost certainly not going to be found. Deep underground testing is the only possibility for finding life on Mars.

The mass media often oversimplifies what it takes to make life possible on a planet. This oversimplification continues to be bombarded by the facts. Just being in the zone where water can exist as a liquid, called the “habitable zone,” doesn’t qualify a planet as a dwelling place for life. The “uninhabitable zone” keeps getting larger.

The number of variables that have to be tweaked to allow life continues to grow as scientists make new discoveries. The toxic Martian cocktail is another factor that has generally been ignored. God’s creation shows the hand of a Master Engineer arranging all of the variables that make life possible to create the unique planet on which we live.
–John N. Clayton © 2017

Scientists and God: A Different View

Scientists and God
J. B. S. Haldane in 1914

In each issue of our printed publication, we have a feature called Scientists and God, in which we quote from a leading scientist who is also a believer in God. Today I would like to do something a little different. I want to quote the words of a leading scientist who was not a believer.

J. B. S. Haldane (1892–1964) was a British geneticist and evolutionary biologist. He was also an outspoken atheist and a Marxist. Because of the political controversy caused by his Marxist ideology, he left England in 1956 and spent the remainder of his life in India.

Haldane was a brilliant man who made contributions in the areas of genetics, evolutionary biology, and mathematics. In many ways, he was ahead of his time. He proposed the central ideas of in vitro fertilization. He was the first to suggest human cloning. In fact, he coined the use of the term “clone” for that purpose. He also helped to create the science of population genetics.

Haldane proposed correctly that sickle-cell disease gives immunity to malaria. He prepared gene maps for color-blindness and hemophilia. Nobel Prize winning biologist Peter Medawar called Haldane “the cleverest man I ever knew.”

In 1929, Haldane introduced the “Primordial Soup Theory,” which said that life began on the early Earth in a chemical soup where the elements of life came together. That theory became the leading concept of abiogenesis–the idea of life coming from non-living matter by a natural process. Haldane’s theory led to the famous Miller-Urey experiment in 1952. In that experiment, Stanley Miller created a sealed container with the chemicals thought to have been part of the early atmosphere of Earth. He subjected the chemicals to an electric spark and collected some amino acids which are the building blocks of proteins. The news media went wild over “creating life in the laboratory,” but that was an example of media exaggeration–or as it would be called today “fake news.”

Incidentally, science has since shown that the Miller-Urey experiment did not emulate the conditions or chemicals of the early Earth and therefore is not a valid demonstration of the first step in abiogenesis. However, it is still shown to students in school textbooks because science has not produced anything better, and it is easy to understand. Today’s attempts at abiogenesis are far more complex, proving that it takes great intelligence and carefully controlled lab conditions to produce even the basic building blocks of life. In other words, it takes intelligence to create life, which has been our message for many years.

Haldane wrote numerous books presenting his ideas and defending Darwinism. In 1949 he debated British ornithologist Douglas Dewar on the topic “Is Evolution a Myth?” In that debate, Haldane said that evolution would not be capable of producing “various mechanisms, such as the wheel and magnet, which would be useless till fairly perfect.” In other words, if those mechanisms could be found in living organisms it would be an indication that evolution did not create those organisms.

Since that debate, we have found magnets in anaerobic bacteria which are considered to be the most “primitive” forms of life. The sightless, single-celled magnetotactic bacteria consume iron and produce magnets which they use to guide them to anaerobic areas that are safe for them to live. The magnets they produce are better for some scientific purposes than what humans can produce in the laboratory. Turtles, birds, and other more advanced animals also use magnets for navigation. Wheels can also be found in living organisms. As Janine M. Benyus (another Darwinist) wrote in her book titled Biomimicry, “Even the wheel, which we always took to be a uniquely human creation, has been found in the tiny rotary motor that propels the flagellum of the world’s most ancient bacteria.”

So wheels and magnets are found in the most “primitive” and “ancient” of single-celled bacteria. If that 1949 debate were taking place today, I doubt if J. B. S. Haldane would say that those mechanisms could disprove evolution. On the subject of Scientists and God, there are many views. Our view is that those mechanisms found in bacteria indicate an intelligent Creator who understood magnets and wheels long before humans did.
–Roland Earnst © 2017

Supreme Court Decision vs. Atheist Foolishness

Supreme Court Decision on Church Playground
Sometimes when atheists attack churches and people who believe in God, their arguments border nonsense. In an earlier post, we told about a state program for child safety in Missouri that was denied to a church solely because it was a church. A Supreme Court decision finally settled the matter.

The state had instituted a grant program which allowed owners of playgrounds to make them safer by purchasing rubberized playground surface material made from recycled tires. In 2012 Trinity Lutheran Child Learning Center in Columbia, Missouri, needed to replace the gravel on their playground with the safer material. The state denied their grant application saying that public funds cannot be given to religious organizations according to the Missouri state constitution. The case went to an appeals court where it ended in a tie vote. It was then appealed to the U.S. Supreme Court. On June 26, 2017, the court decided in favor of the church.

This case may sound frivolous, but it is an important issue. Churches run food banks, women’s shelters, street kitchens, relief agencies, counseling centers, and many other programs to help people. Churches provide those services more efficiently at less cost than government programs. The services that churches provide relieves the burden from taxpayers while providing more help for more people in need. If the government penalizes the work of the churches simply because they are “religious,” everyone suffers. Atheists provide none of those services to any great extent, if at all. We see foolish cases like this one increasing because of blind hatred for God.

The Alliance Defending Freedom represented Trinity Lutheran in this case, and they argued that Missouri’s “…religious exclusion sends a message that Trinity’s children are less worthy of protection simply because they play on a playground owned by a church.” The ADF also stated that “People of faith shouldn’t be treated like second-class citizens–every child’s safety matters. The government shouldn’t make children in religious preschools less safe on playgrounds than other children.”

You will find the details of the ruling on the SCOTUS Blog. The complete text of the Supreme Court decision is posted on the court opinions page as Trinity Lutheran Church of Columbia, Inc. vs. Comer.
–John N. Clayton © 2017

Moderate Drinking and the Brain

Moderate Drinking
Does moderate drinking cause physiological problems? We see a lot of misleading information in the media about the effects of alcohol. There have been studies linking consumption of alcohol to longer life expectancy. We have pointed out that the agents causing health benefits from drinking wine are the flavonoids in grapes. Alcohol is not the agent of health benefits.

A recent study published in the British Medical Journal reports that long-term studies show a negative effect in the brain of moderate drinkers. The study defined moderate drinking as weekly doses of 8 to 12 small glasses of wine, bottles of beer, or shots of liquor. It followed 527 British citizens for 30 years, and the subjects were “predominantly white middle-class men.”

The study showed that moderate drinkers were more likely than nondrinkers to develop brain changes that might precede or accompany memory loss. They also were more likely to show a more rapid decline in a language fluency test. Moderate drinkers were three times more likely than nondrinkers to show shrinkage of the hippocampus area of the brain–a change that accompanies dementia. Heavy drinkers showed the most shrinkage.

Claims that moderate drinking is healthy and improves the quality of life are simply not true. Alcohol continues to be the most destructive recreational drug.
Reported in USA Today, June 7, 2017, page B1.
–John N. Clayton © 2017

Babies and Pain–A New Study

Babies and Pain
One of the areas of medicine that seems to be neglected is pain management. That is true of all ages, but one of the least studied age groups for investigating the experience of pain is what infants experience before, during, and after birth. There are special challenges when studying babies and pain.

Pain assessment in babies is difficult because they don’t talk and it is difficult to know whether they are in pain or whether their crying is due to something else. The use of facial expressions or body jerking or wiggling is likely to be very misleading. The May 3 issue of Science Translational Medicine carried a report on the use of electroencephalography (or EEG). Doctors used a special device called a Cz electrode to pick up brain waves when the baby experienced a painful event such as having its heel lanced to draw blood. The electroencephalogram showed a neural spike immediately after having the poke to the heel.

Babies born prematurely between 34 and 36 weeks of gestation show the same kind of responses to pain. Not all babies have exactly the same response, but there is enough consistency to believe that the babies do in fact sense pain. The babies did not show the same response to loud noises, flashing lights, or non-painful touches.

This research suggests a number of things. Procedures done on babies that could cause pain in an adult seem to be very likely to cause pain in a baby. The use of painkillers and the effect of medical treatment on the brain of a small child needs to be more carefully studied. Medical studies of babies and pain must proceed with care.

The question of whether abortion causes pain in the baby must be considered. The answer seems to be that babies do sense pain and that is also true of premature babies. Women who are considering medical procedures on their babies and especially abortion need to know what the evidence shows.
Reference: Science News, June 10, 2017, page 8.
–John N. Clayton © 2017