Left-Handedness of Proteins and Amino Acids

Left-Handedness of Proteins and Amino Acids
Left-Handedness of Proteins and Amino Acids
Left-Handed Amino Acid Glutamic Acid Molecule

About 9.2 percent of people are left-handed. In other words, less than 10 percent of humans exhibit left-handedness. However, the proteins in living organisms are 100 percent left-handed. I know proteins don’t have hands, but using the term “handedness” helps to explain how proteins are structured. Proteins are made from amino acids, which fold into left-handed shapes that enable their functions in living beings. These proteins are composed of amino acids, which are also left-handed.

This handedness is more accurately called “chirality.” There are over 500 different amino acids, and they exhibit both left and right chirality. However , only 22 of them are used to make proteins, and their chirality is all left-handed. This creates a mystery. If amino acids existed on early Earth in equal amounts of right- and left-handed forms, and life requires only left chirality, how could life have formed spontaneously? Some thus-far unexplained force would have to select only left-handed amino acids to come together to get life started. Robert F. Service, writing on science. org, called this “an enduring mystery.”

Scientists have proposed several ideas to explain why proteins are left-handed. Some suggest meteorites delivered left-handed amino acids to early Earth. It appears that meteorites are rich in these amino acids, likely due to exposure to polarized light. Another hypothesis is that magnetic fields on early Earth twisted the biomolecules. Robert Service asks, “But even if some external force imparted an initial bias, what propagated it?”

Gerald Joyce, a chemist specializing in the origins of life and president of the Salk Institute for Biological Studies, said, “Perhaps it was just a statistical coin flip that caused an original bias toward building blocks of one-handedness to form. But once that coin flipped, it caused other coins to flip.” Those of us who believe in a Creator are often accused of using a “God-of-the-gaps” explanation for life’s mysteries. To me, this explanation for the left-handedness of proteins sounds like a “coin-flip-of-the-gaps.”

— Roland Earnst © 2025

Reference: science.org and Science magazine, Vol 383, Issue 6686

Amazing Human Body Works

Amazing Human BodyThe cover story of the June (2019) issue of Reader’s Digest lists 50 features of your amazing human body. The article gives some evolutionary guesses as to how some of those features could have developed. We thought it was especially interesting that science has not explained nine of the 50:

1-The uvula at the back of your throat.
2-Hypnic jerks that 70% of people feel right before they go to sleep.
3-The “Old Person Smell” – an odor that comes from older people that young and middle-aged people don’t have.
4-Blood types.
5-Eyelid twitching.
6-Yawning.
7-Handedness and why 90% of us are right-handed.
8-Fingerprints.
9-Mesentery – a recently discovered membrane that is two feet long and spreads out like a fan in our digestive system.

David said it best: “I will praise you, for I am fearfully and wonderfully made: marvelous are your works…” (Psalms 139:14). In spite of all of our medical advances, we still are trying to understand how the amazing human body works. Understanding how our bodies work allows us to take better care of them. It also helps us to treat what goes wrong, which is often caused by our own abuse.
— John N. Clayton © 2019