Origin of Life Problems Admitted

Wing Challenge to Origin of Life
One of the more honest and fair writers in modern scientific publications is Dr. Bob Berman. He has a regular column in Astronomy magazine and an interesting website. In the September 2017 issue of Astronomy (page 10), he has an outstanding brief review of the problems involved in trying to explain the origin of life. He begins by pointing out that the definition of “life” has been an issue because of questions such as whether or not a virus is alive. Viruses have no metabolism, they don’t feed or breathe, and yet they reproduce.

Berman then reviews some of the parameters necessary to consider when addressing the origin of life. Chirality is a major issue because amino acids that make up proteins come in right- and left-handed versions. Life on Earth is made up of only left-handed amino acids. Sugars used by the proteins are limited to the right-handed direction, and so is DNA. The wrong chirality just will not work to support life, so how could nature sort out the chirality? If life is easy to produce, why don’t we see it coming into existence all over the Earth? The “amoeba-to-man” model assumes that it only happened once, which conflicts with the view that life is abundant in the cosmos.

What is especially interesting is that Berman raises questions about the ability of evolution to explain on a chance basis some of the designs we see in living things. He uses the example of the airfoil that all flying forms of life have. The upper surface is convex using the Bernoulli effect to produce lift. The earliest bird and the flying reptiles all had a wing design that works. Trial and error would not work well to explain how the wing design would come into existence by chance. Berman points out that “some 400,000 cells would all have to simultaneously mutate in just the right way to create a properly shaped wing. This defies an evolutionary hypothesis.”

Berman concludes with the statement, “I’m not invoking spirituality, merely that the effect of random collisions and mutations is not always a workable answer. So perhaps nature is inherently smart.” I would suggest that wing design is just one of a massive number of design features that allow life to exist.

Berman quotes Francis Crick, the co-discoverer of DNA’s double helix as saying that the origin of life is “almost a miracle, so many are the conditions which would have had to have been satisfied to get it going.” We don’t invent a “god” to explain these things, but we would point to these things as one more evidence that there is a God and that blind chance is not a good designer of the complexity we see in the world around us.
–John N. Clayton © 2017

Genetically Modified Human Embryos

Genetically Modified Human Embryos
Shoukhrat Mitalipov

Chinese scientists have conducted at least three experiments to create genetically modified human embryos. Now, MIT Technology Review reports that a team of scientists in the United States has edited the DNA of human embryos. The experiment was performed at Oregon Health and Science University, a public university in Portland, under the leadership of Shoukhrat Mitalipov. It is apparently the first time this has been done in the United States, and it involved a greater number of embryos than the Chinese experiments.

Mitalipov, who was born in the former Soviet Union and received his Ph.D. in Moscow, came to the U.S. because there was a lack of funding for genetic experimentation in his home country. Since coming to the U.S. he has cloned monkeys and human embryos. This is the first time for editing the DNA of a human embryo.

The scientists used a gene-editing tool called CRISPR, which we have reported on before. The goal of the experiment is supposed to be to find a way to correct genetic defects in humans. The sperm used to fertilize the embryos came from a man with a genetic defect. The embryos were destroyed after a few days because in the United States it is illegal to allow genetically modified human embryos to develop into full-term babies.

In February the U.S. National Academy of Sciences gave support for creating gene-edited babies if the purpose is the elimination of serious genetic diseases. Genetically modified human embryos can develop into gene-modified humans who will pass on the genetic changes to their offspring. This may offer hope for eliminating genetic defects. However, it also has implications for the nightmare scenarios of a science-fiction movie. When humans start to play God by manipulating the DNA of our children, what if they make a disastrous mistake? The United States Intelligence Agency listed CRISPR as a potential “weapon of mass destruction.”

Beyond the implications of Frankenstein-like creatures, there is the aspect of “designer children.” DNA could potentially be edited to select the sex, physical features, and even intelligence of an unborn child. So far that is illegal in the United States, but not in other countries. One of the problems the Chinese experimenters encountered is called “mosaicism,” in which the change to the DNA is not taken on by all of the cells. The implications of a person with multiple DNA codes in different cells is not fully understood. Other CRISPR errors referred to as “off target” effects could result in serious genetic defects. Mitalipov’s team claims to have those problems under control.

The report from this U.S. experiment should be published soon, and it will certainly be in the news. Christians should be concerned about where this is leading. Do humans have the right to play God with our DNA? What could be the result of “off target” mistakes? What about the ethics of creating human embryos for experimentation and then destroying them? Do the possible breakthroughs in the elimination of genetic diseases outweigh the dangers? What about the moral cost to our society as we go down this road?

One thing you can be sure of is that humans will continue to create genetically modified human embryos. If it doesn’t happen in the United States, it will happen in other countries. You can also be sure that there will be some scientists who will do so with less than pure motives. In Mary Shelley’s classic book telling about a scientist’s desire to create a new species, Victor Frankenstein said, “A new species would bless me as its creator and source; many happy and excellent natures would owe their being to me. No father could claim the gratitude of his child so completely as I should deserve theirs.” The power to become a god creating new species of humans can overpower pure motives as it did with Victor Frankenstein. The outcome could be even more tragic than in the novel.

It’s time to consider the many times the Bible tells of the value of every human being and the love God has for us. Many people have become concerned about GMO’s (Genetically Modified Organisms) in food. How much more should we be concerned about Genetically Modified Humans?
–Roland Earnst © 2017